In the case of company takeovers, a comprehensive company valuation is an indispensable prerequisite for determining the actual value of the company. This is particularly important in times of increased company takeovers. Classical valuation methods, however, only take into account the financial situation, and other factors are not usually taken into account. The question therefore arises as to how a more comprehensive company valuation can be ensured. Theoretical concepts from business administration form a suitable basis to carry out a more comprehensive, holistic view of the company. This paper develops a comprehensive methodological approach for the valuation of growth companies. Aspects of the company to be evaluated that go beyond the financial aspects are included. Strategy, technology, organization and management skills as well as cooperation with other companies are fundamental components of this valuation approach in addition to the financial situation. A practical company example from the biotechnology sector is used to illustrate the application of the valuation approach.